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Coursework

Koch's Postulates [2017 EM]
작성자 MML 작성일 17-08-21 20:51 조회 4,254

What happened to Koch’s postulates in diarrhoea? 

Environ. Microbiol. (2017)


Loss of a physiological commensal gut microbiota equilibrium (‘dysbiosis’) is an important co-factor for some bacterial pathogens to induce diarrhoea.


Koch’s hypothesis "1 pathogen + 1 host = 1 disease" is therefore better formulated as 

"X (pathogen[s]) + Y (local milieu) + Z (individual host susceptibility) = disease".

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